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What is Glibenclamide?

Glibenclamide, also known as glyburide, is classified as a sulphonylurea, or antidiabetic drug that helps control blood sugar levels. Glibenclamide is used in cases where insulin is deficient in the body, to help stimulate pancreatic cells to produce more insulin.

Glibenclamide is sold under the brand names Diabeta, Glynase and Micronase. It is an oral medication sold in tablet form.

Uses for Glibenclamide

Glibenclamide is used in the treatment of Type 2 Diabetes to control blood sugar levels. It is considered a treatment option for those who are not overweight, and for those who have not responded to metformin and who were unable to control their blood sugar with diet and exercise. It is often used in combination with other antidiabetic medicines.

Possible Side Effects of Glibenclamide

Side effects of glibenclamide include diarrhea, constipation, vomiting, nausea and abdominal pain, hypoglycemia (low blood glucose levels), liver dysfunction, weight gain, skin rashes, hepatitis (liver inflammation, cholestatic jaundice and change in blood cell levels.

Glibenclamide can also interact with other medications, including ACE inhibitors, anabolic steroids, insulin and more, so it's important to provide a full medication to your doctor when considering glibenclamide.

It's also advised that glibenclamide not be used during pregnancy, unless advised and closely monitored by a doctor. Be sure to tell your doctor if you are pregnant or are thinking of becoming pregnant. Glibenclamide can also pass through breast milk, which could cause blood sugar levels to drop in infants who are nursing, and so should not be used when breastfeeding.

Warnings About Glibenclamide

The information listed here regarding glibenclamide is for reference purposes only, and should not be used in place of medical advice. Always consult a doctor before introducing a new medication into your health regimen for correct dosage and treatment information, proper monitoring and further side effects or possible interactions with other medications.

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